Dr Paddy Barrett

Dr Paddy Barrett

APOE4 & Cardiovascular Risk

Why the APOE4 gene variant does more than increase your risk of dementia.

Dr Paddy Barrett's avatar
Dr Paddy Barrett
Aug 23, 2023
∙ Paid

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia.

There are three primary variants of APOE - APOE2, APOE3 & APOE4.

Everyone has two separate copies. One inherited from either parent.

As a result, there are six different possible combinations.

APOE 2/2, 2/3, 2/4, 3/3, 3/4, 4/…

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